ORGN 651 |
| Iejimalides constitute a new family of marine natural products with remarkable and unprecedented biological properties. Furthermore, their unique structural features: 24-membered ring macrolactone, six stereocenters and four dienic systems make it a challenging target for organic chemists. Our efforts towards the total synthesis of Iejimalide B based on alkene metathesis and metal catalyzed Csp2-Csp2 couplings will be presented.
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Total Synthesis of Complex Molecules
8:00 AM-12:00 PM, Wednesday, 13 September 2006 Moscone Center -- Room 132, Oral
Division of Organic Chemistry |
