Towards the synthesis of 5,6,7,8-tetrahydroacridin-4-ol and quinolin-8-ol derived tripodal receptors

ORGN 767

Elleanor Rio C. Andaya, andayae@unr.nevada.edu and Thomas W. Bell. Department of Chemistry, University of Nevada Reno, 1664 North Virginia St., Mail Stop 216, Reno, NV 89557

Tripodal receptors have been designed to bind and to detect several types of analytes, such as alkylammonium and large metal ions. Several tripodal receptors derived from 8-hydroxyquinoline compounds are targeted for synthesis. The tripodal receptors are of two types, tris(o-hydroxyphenyl)methanes and 1-azatryptycenes. These receptors are predicted to have large cavities, big enough to fit large metals, such as actinides and lanthanides. In this poster, details of the progress toward the synthesis of these receptors are presented.