ORGN 434 |
| It has been demonstrated that 1,2,3-triazolo[1,5-a]pyridines 1 may serve as stable, readily available and effective precursors for Rh-carbenoids containing pyridyl substituent. In reaction with terminal alkynes, depending upon conditions, triazole 1 either gives [2+1] cycloaddition product, cyclopropene 2, or undergoes unprecedented transannulation reaction to form indolizine 3 directly. Additionally, it has been found that 2 in a presence of Cu(I) salts can be efficiently transformed into 3. The scope, limitations and possible mechanisms of these novel transformations will be discussed.
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Modern Acetylene Chemistry
8:00 PM-10:00 PM, Tuesday, 12 September 2006 Moscone Center -- Hall D, Poster
Division of Organic Chemistry |
