ORGN 145 |
| A new procedure has been developed for direct, asymmetric aldol reactions of alpha,alpha-dialkyl aldehydes with aromatic aldehydes which produce quaternary carbon-containing beta-hydroxy carbonyl compounds. The processes, promoted by an organocatalyst (S) pyrrolidine sulfonamide, take place in high yields with exceptionally high levels of enantioselectivities. |
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Asymmetric Reactions and Syntheses, Metal-Mediated Reactions, Combinatorial, Parallel, and Solid-Phase Chemistry
8:00 PM-10:00 PM, Sunday, 10 September 2006 Moscone Center -- Hall D, Poster
Division of Organic Chemistry |