Facile synthesis of isodamascone and its analogs

ORGN 541

D. W. Rangnekar, dwrangnekar@yahoo.com1, V. S. Kulkarni, drvskulkarni@rediffmail.com1, P. V. Ranade1, and R. W. Sabnis, ramsabnis@yahoo.com2. (1) Institute of Chemical Technology, University of Mumbai, Matunga, Mumbai, 400019, India, (2) R & D, Ascadia Inc, 3947 Thames Avenue, Eagan, MN 55123
Synthesis of isodamascone and its analogs, the commercially important aroma compounds, have been accomplished from the readily available 1,5,5-trimethyl-2-cyclohexen-1-ol via a short, facile and simple sequence of reactions in excellent yields.