ORGN 107 |
| Organocatalysis has seen limited application in radical chemistry. Herein we wish to report an efficient SET oxidation of chiral enamines with catalytic FeCl3 and application of the resulting alpha-iminium radicals in enantioselective C-O bond formation using TEMPO. The effect of the catalyst, SET reagent, solvent, and reaction conditions on the chemical efficiency and enantioselectivity will be discussed. Substrate scope and approaches to tandem bond formation will also be presented.
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Asymmetric Reactions and Syntheses, Metal-Mediated Reactions, Combinatorial, Parallel, and Solid-Phase Chemistry
8:00 PM-10:00 PM, Sunday, 10 September 2006 Moscone Center -- Hall D, Poster
Sci-Mix
Division of Organic Chemistry |
