ORGN 475 |
| Diverse applications require access to water-soluble, bioconjugatable porphyrins. A symmetrically branched alkyl chain (“swallowtail”) bearing a charged group at each terminus imparts high water solubility (~20 mM) to a porphyrin upon attachment at one of the meso positions. The charged groups project above and below the plane of the porphyrin macrocycle. Here we present the synthesis of a water-soluble bioconjugatable porphyrin equipped with a bis-phosphonate swallowtail moiety and an iodoacetamide unit.
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New Reactions and Methodology, Heterocycles and Aromatics, Bioorganic Chemistry
8:00 PM-10:00 PM, Tuesday, 12 September 2006 Moscone Center -- Hall D, Poster
Division of Organic Chemistry |
