ORGN 652 |
| Due to its extraordinary biological activity and a daunting architecture, amphidinolide H remains a challenging target for synthetic organic chemists. We have thus embarked on a quest to develop an efficient total synthesis. The stereoselective construction of the C1-C13 and the C14-C26 fragments, the successful installation of the trisubstituted diene unit and our efforts to complete the total synthesis will be presented.
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Total Synthesis of Complex Molecules
8:00 AM-12:00 PM, Wednesday, 13 September 2006 Moscone Center -- Room 132, Oral
Division of Organic Chemistry |
