ORGN 22 |
| Asymmetric Michael reactions catalyzed by a chiral bicyclic guanidine are described. A variety of 1,3-dicarbonyl compounds, including S,S'-dialkyl dithiomalonates, dialkyl malonates, 1,3-diketones and benzoylacetate, can function as the Michael donors in the reaction with various N-alkyl maleimides and 2-cyclopenten-1-one, giving high enantioselectivities and yields.
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Asymmetric Reactions and Syntheses
8:00 AM-12:20 PM, Sunday, 10 September 2006 Moscone Center -- Room 131, Oral
Division of Organic Chemistry |
