ORGN 931 |
| Chlorins bearing few or no substituents are valuable benchmarks for spectroscopic characterization and fundamental studies of reactivity. Several routes were investigated for the preparation of chlorins bearing only a 10-substituent or lacking any meso- or beta-pyrrolic substituents. The synthetic approach required preparation of the appropriately functionalized tetrahydrodipyrrin (1, Western half) and dipyrromethane (2, Eastern half). The best method entailed condensation of a 2,3,4,5-tetrahydro-1,3,3-trimethyldipyrrin (1, X = H) and a 9-bromo-1-formyldipyrromethane (2, Y = CHO, Z = Br).
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Heterocycles and Aromatics
1:00 PM-4:40 PM, Thursday, 14 September 2006 Moscone Center -- Room 135, Oral
Division of Organic Chemistry |
