Catalytic highly enantioselective C-H oxidation of vic-diols with Shi's oxazolindione dioxiranes

ORGN 161

Cong-Gui Zhao, cong.zhao@utsa.edu and Kavitha Jakka. Department of Chemistry, University of Texas at San Antonio, 6900 N. Loop 1604 W, San Antonio, TX 78249
The first dioxiranes-mediated catalytic highly enantioselective C-H oxidation protocol was realized with the Shi's oxazolidione ketone catalysts. Very good enantioselectivity (up to 92% ee) may be obtained for both asymmetrization of meso vic-diols and kinetic resolution of racemic vic-diols.

 

Asymmetric Reactions and Syntheses, Metal-Mediated Reactions, Combinatorial, Parallel, and Solid-Phase Chemistry
8:00 PM-10:00 PM, Sunday, 10 September 2006 Moscone Center -- Hall D, Poster

Division of Organic Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006