ORGN 498 |
| We have developed an organocatalytic highly enantioselective cross aldol reaction of á-ketophosphonates and ketones for the synthesis of optically active á-hydroxy phosphonates using L-proline or L-prolinamide as the catalyst. The regio-, diastereo-, and enantioselectivity of this novel cross aldol reactions will be discussed. |
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New Reactions and Methodology, Heterocycles and Aromatics, Bioorganic Chemistry
8:00 PM-10:00 PM, Tuesday, 12 September 2006 Moscone Center -- Hall D, Poster
Division of Organic Chemistry |