Morphing natural architectures into metal complexes with novel properties: From metallo-nucleic acids to metals in protein kinase inhibitors

ORGN 290

Eric Meggers, meggers@sas.upenn.edu, Department of Chemistry, University of Pennsylvania, 231 S. 34th Street, Philadelphia, PA 19104
Coordination compounds are distinguished by their structural diversity, unusual reactivities, and extraordinary abilities to catalyze chemical transformations. The presentation demonstrates how these properties can lead to new research opportunities at the interface of bioorganic and bioinorganic chemistry, including DNA-inspired artificial metallo-nucleic acids, metal complexes that mimic the structure and function of natural products, and coordination compounds that serve as miniature enzymes and are capable of executing their catalytic reactions under physiological conditions.
 

Tetrahedron Prize for Creativity in Organic Chemistry
1:00 PM-5:02 PM, Monday, 11 September 2006 Moscone Center -- Room 134, Oral

Division of Organic Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006