ORGN 698 |
| The functional-architecture of complex natural products encodes a compendium of biological regulators. Through classical advances, total synthesis has been elaborated to provide access to rare materials as well as to advance synthetic methodology. Recent accolades in the large-scale synthesis of complex natural products provide unequivocal support for this achievement. While often not recognized, total synthesis is a tool that can be used synonymously with biological science. A series of collaborative case studies will be presented that illustrate how route-development can be tailored to guide the elucidation of a natural product's mechanism of action. Lessons derived from this effort provide advance support for the implementation of total synthesis as a tactical maneuver for developing and understanding of small molecule biology.
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Total Synthesis of Complex Molecules
1:00 PM-5:00 PM, Wednesday, 13 September 2006 Moscone Center -- Room 132, Oral
Division of Organic Chemistry |
