Synthesis of a natural insect repellent isolated from thrips

ORGN 671

Rene Csuk, rene.csuk@chemie.uni-halle.de and Anja Niesen. Institute of Organic Chemistry, Martin-Luther-University Halle-Wittenberg, Kurt-Mothes-Str. 2, D-06120 Halle (Saale), Germany
The pricipal approach to prevention of vector-borne diseases is avoidance; thus, the use of repellents against biting arthropods is highly recommended. GC-MS analysis of the low volatile defensive secretion from Suocerathrips linguis (a small inscet living on leaves of Sanseveria plants) revealed the presence of an hitherto unkown repellent, i.e. (11 Z)-11,19 eicosadienyl acetate (1). A convenient, high yield procedure for the synthesis of (1) has been developed. Compound (1) shows strong repellent activity against ants, whereas its (E)-analogue showed no repellent activity at all.