ORGN 444 |
| 1-Trimethylgermyl-1-alkynes easily prepared by the deprotonation of the terminal alkynes with n-butyllithium followed by reaction with trimethylgermanium bromide readily undergo dihydroboration with two equivalents of dichloroborane-dioxane complex in dichloromethane at room temperature for 12 h. The resulting dihydroborated products are reacted with water at 0 oC for half an hour to provide the corresponding boronic acids. These are then reacted with 1,3-propane diol in n-pentane to provide the corresponding boronate esters in good yields (72%-82%). The structures of these boronate esters are confirmed by NMR spectral data.
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Modern Acetylene Chemistry
8:00 PM-10:00 PM, Tuesday, 12 September 2006 Moscone Center -- Hall D, Poster
Division of Organic Chemistry |