ORGN 14 |
| The emerging new examples of alkyl-alkyl cross-coupling reactions suggest that transition-metals can be used to effectively couple organic substrates normally thought too susceptible to competing beta-hydride elimination reactions. In the past year, the first examples of asymmetric cross-coupling of alkyl electrophiles have even appeared in the literature. A number of issues still remain to be addressed, however, before we can rationally modify current catalysts to increase the scope and efficiency of the cross-couplings. A detailed understanding of the mechanism of catalysis, in particular, will help push this field ahead in sophistication, and a number of studies in this regard will be presented.
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Young Investigators Symposium
8:25 AM-12:00 PM, Sunday, 10 September 2006 Moscone Center -- Room 135, Oral
Division of Organic Chemistry |
