ORGN 937 |
| Enzymes are arguably the most important class of proteins, practically involved in every biological process in the cellular machinery. Many classes of enzymes, e.g. proteases, kinases and phosphatases, are linked to a variety of diseases. We are interested in what is called “Catalomics” - the large-scale study of enzymes (and, in future, other catalytic molecules at the organism scale) by using a variety of chemical approaches developed both in our own laboratories and by others. Research in all aspects of enzymes are currently being pursued, ranging from the development if novel techniques for potential high-throughput identifications of enzymes, the detailed studies of enzyme reactions and kinetics, as well the way by which enzymes work inside a living organism, to the design, synthesis and screening of biologically interesting molecules which may module (e.g. activate or inhibit) enzyme activities. The ultimate aim of our research is to develop potential enzyme-targeting, drug candidates that help in the cure of major human diseases. |
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Proteins, Peptides, Amino Acids, and Enzyme Inhibitors
1:00 PM-5:00 PM, Thursday, 14 September 2006 Moscone Center -- Room 131, Oral
Division of Organic Chemistry |