ORGN 476 |
| Bootstrapping provides a statistical technique to test whether or not the variations in a series of product yields are independent of the order of the observations. The response variable of interest is the product yield of oxazoline and experiments were carried out at various levels of independent variables: temperature, concentration of amino alcohol, and concentration of toluenesulfonic acid. Oxazolines have been used as a protecting group of carboxylic acids and, more recently, used as ligands for transition metals. Oxazolines were synthesized from the condensation between an amino alcohol and carboxylic acid. The number of peaks and troughs in the series of product yield is found. A turning point test, a run test and a rank correlation test are carried out to test for the randomness of fluctuations in product yield. A second data set consisting of total nickel content (water quality data) was also used to illustrate the procedure. |
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New Reactions and Methodology, Heterocycles and Aromatics, Bioorganic Chemistry
8:00 PM-10:00 PM, Tuesday, 12 September 2006 Moscone Center -- Hall D, Poster
Division of Organic Chemistry |