| MEDI | Wednesday, 29 March 2006 | ||
1:30 PM-5:10 PM Georgia World Congress Center -- Georgia Ballroom 3, Oral | |||
p53 Inactivation and Reactivation by Synthetic Organic Molecules | |||
| Organizer: | Daniel H. Appella | ||
| 1:30 PM | Introductory Remarks | ||
| 1:35 PM | 227 | Mapping the p53-hdm2 protein-protein interaction by structure-guided peptidomimetics Patrick Chene, Pascal Furet, Carlos Garcia-Echeverria | |
| 2:10 PM | 228 | Small-molecule antagonists of the p53-mdm2 interaction Binh T. Vu, Bradford Graves, Lyubomir T. Vassilev, Daisy Carvajal, Zoran Filipovic, Christine Lukacs, Christian Klein, Ursula Kammlott, Frank Podlaski, Weiguo Qing, Kathryn Packman, Norman Kong, Emily Liu, Kathleen Dillon, Anthony Specian Jr., Gerald Kaplan, Sung-Sau So, Don Emerson, David Fry, Kyungjin Kim, Steven G. Mischke, Bingbing Wang, John Roberts, Nader Fotouhi | |
| 2:45 PM | 229 | Computational Studies and peptidomimetic design for the p53-HDM2 complex Heather A. Carlson, Haizhen Zhong, Anna L. Bowman | |
| 3:20 PM | 230 | Discovery and structure-based design of benzodiazepinedione inhibitors of the HDM2:p53 complex Bruce L. Grasberger, Tianbao Lu, Juan Jose Marugan, Daniel J. Parks, Carsten Schubert, Holly K. Koblish, Maxwell D. Cummings, Kristi A. Leonard, Pierre Raboisson, Karen L. Milkiewicz, Raul R. Calvo, Louis V. LaFrance, Robert R. Donatelli, Diane Maguire, Theodore E. Carver, Jennifer Lattanze, Carol F. Franks, Shuyuan Zhao, Kannan Ramachandren, Ingrid C. Deckman, Anna C. Maroney | |
| 3:55 PM | 231 | Beta-hairpin protein epitope mimetics that inhibit the p53-HDM2 interaction John Anthony Robinson | |
| 4:35 PM | Concluding Remarks | ||
Symposium Grid -- Division of Medicinal Chemistry -- Session Listing
Symposium Grid -- Drug Discovery -- Session Listing
The 231st ACS National Meeting, Atlanta, GA, March 26-30, 2006