ORGN 101 |
| The amide resulting from the combination of 1-adamantanamine and adamantane-1-carboxamide was prepared at 22º in tetramethylenesulfone solution. From solution to crystalline product formation less than a minute elapsed. First obtained was three adamantonium carboxylate salt which stemmed from hydrogen transfer from the carboxyl to the amino-group. When the salt was warmed to 60º white needles of the corresponding amide, N-adamantyl-1-adamamantanamide, formed in about ten seconds |
|
Asymmetric Reactions and Syntheses, Physical Organic Chemistry, Combinatorial Chemistry, Total Synthesis
8:00 PM-10:00 PM, Sunday, 26 March 2006 Georgia World Congress Center -- Ex. Hall B4, Poster
Division of Organic Chemistry |