Synthesis and evaluation of tetrasodium 2,3,4,5-O-sulfonato-poly(4-alkyl-4-azaheptamethylene-D-glucaramides) as pseudostationary phases for the electrokinetic separation of aromatic-aliphatic ketones and peptides

CARB 57

Travis T. Denton, travis.denton@umontana.edu1, Erika Rauk2, Christopher P. Palmer, christopher.palmer@umontana.edu2, and Donald E. Kiely, donald.kiely@umontana.edu1. (1) Shafizadeh Rocky Mountain Center for Wood and Carbohydrate Chemistry, Department of Chemistry, The University of Montana, 32 Campus Dr, Missoula, MT 59812, (2) Department of Chemistry, University of Montana, Missoula, MT 59812-1006
Poly(4-alkyl-4-azaheptamethylene-D-glucaramides), synthesized by the polycondensation of 4-alkyl-4-azaheptamethylene-1,4-diamines and methyl glucarate-1,4-lactone, were poly-O-sulfonated by treatment with a sulfur trioxide-triethylamine complex in DMF at elevated temperatures to afford tetratriethylammonium 2,3,4,5-O-sulfonato-poly(4-alkyl-4-azaheptamethylene-D-glucaramides). The triethylammonium cations were exchanged for sodium by treatment of the sulfonated polymers with Amberlite IR-120(Plus) sodium form ion exchange resin to afford the tetrasodium 2,3,4,5-O-sulfonato-poly(4-alkyl-4-azaheptamethylene-D-glucaramides). The synthesis of the polymeric pseudostationary phases and their performance in the electrokinetic separation of aromatic-aliphatic ketones and peptides will be discussed.

 

General Posters
6:00 PM-8:00 PM, Tuesday, 28 March 2006 Georgia World Congress Center -- Ex. Hall B4, Poster

Sci-Mix
8:00 PM-10:00 PM, Monday, 27 March 2006 Georgia World Congress Center -- Ex. Hall B4, Sci-Mix

Division of Carbohydrate Chemistry

The 231st ACS National Meeting, Atlanta, GA, March 26-30, 2006