Complex nanostructures from biohybrid block copolymers

PMSE 102

Irene C. Reynhout, i.reynhout@science.ru.nl1, Jeroen JLM Cornelissen2, and Roeland JM Nolte2. (1) Institute for Molecules and Materials, Radboud University Nijmegen, Toernooiveld 1, Nijmegen, 6525ED, Netherlands, (2) Department of Organic Chemistry, Radboud University Nijmegen, Toernooiveld 1, Nijmegen, 6525ED, Netherlands
Amphiphiles are an important class of molecules with very interesting properties. Because of their broad range of applications, a lot of research towards the development of new amphiphiles has been carried out. In our group we are focusing on biohybrid amphiphiles of various sizes derived from peptides, proteins and enzymes which assemble in a variety of (functional) structures when dispersed in water. Here, we report on the synthesis and self-assembly behavior of biohybrid triblock copolymers with myoglobin as the hydrophilic biological block. Functionalized polystyrene-polyethylene glycol block copolymers were used as the synthetic block. Preparation of these biohybrid macromolecules was successful and preliminary aggregation studies have been carried out.
 

Polymers, Nanoparticles and Composite Materials in Nanoscience
1:30 PM-4:50 PM, Monday, 27 March 2006 OMNI at CNN Center -- Intl. Blrm D, Oral

Division of Polymeric Materials: Science and Engineering

The 231st ACS National Meeting, Atlanta, GA, March 26-30, 2006