CHED 378 |
| Recent work in our lab has focused on the design and synthesis of oligonucleotides with a unique polyester backbone. This polyester backbone consists of the hydroxy acid 1-hydroxy-3,6,9-trioxa-12-azatetradecan-14-oic acid, where the amine is acylated with a nucleobase acetic acid derivative. We hope the oligo(ethylene glycol)-derived backbone yields oligonucleotides with good solubility in organic solvents and water. This poster reports progress towards the synthesis and characterization of a pair of complementary dinucleotides. |
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Undergraduate Research Poster Session: Organic Chemistry
11:00 AM-1:00 PM, Monday, 27 March 2006 Georgia World Congress Center -- Ex. Hall B4, Poster
Division of Chemical Education |