Ring-closing metathesis approaches to novel S-scaffolds

ORGN 305

Maria del Sol Jiménez, msjimenz@ku.edu and Paul R. Hanson, phanson@ku.edu. Department of Chemistry, University of Kansas, Lawrence, KS 66045-7582
Efforts towards the development of sulfur heterocycles (S-heterocycles) will be reported. This study demonstrates the synthesis of a variety of interesting S-heterocycles by use of ring-closing metathesis. Cyclic S-heterocycles ranging from 5- to 11-membered rings have been obtained in good to excellent yields. In addition, recent routes towards the synthesis of novel sulfonamide sugar (S-sugar) scaffolds and their analogs for future library development will also be described.

 

Combinatorial, Parallel, and Solid-Phase Chemistry
1:00 PM-5:20 PM, Tuesday, 28 March 2006 Georgia World Congress Center -- C302, Oral

Division of Organic Chemistry

The 231st ACS National Meeting, Atlanta, GA, March 26-30, 2006