Investigating the reactivity of aziridinium ions in the presence of reducing agents

CHED 414

Caryn K. Prudenté, prudente@maine.edu and Gail Marie Willette, gailmarie85@hotmail.com. Department of Chemistry, University of Southern Maine, P.O. Box 9300, 96 Falmouth St, Portland, ME 04104
The reactivity of aziridinium ions, with a particular focus on the radical reactions of aziridinium ions, has been investigated. The synthesis of a variety of substituted aziridinium ions has been a significant component of our research. In addition to the previously mentioned component of research, the improvements in the methodology of forming aziridinium ions and radical chemistry methodology have been key focuses. We have explored the radical chemistry of a selected few aziridinium ions and have had relative success. Presently, we are optimizing reaction conditions and continuing in the exploration of the radical chemistry of these ions. This poster will discuss the synthetic schemes, structural analysis, including nuclear magnetic resonance and gas chromatography and mass spectrum, and future avenues of research and application.