ORGN 134 |
| Supported sulfonic acids are in a class of strong acids (pKa <<1) widely used in different fields of synthetic organic chemistry. Their applications are widely known and the various form of the products are used in a large number of settings going from the drug discovery laboratories up to the manufacturing processes. We will present different applications using SiliaBond® Sulfonic Acids to demonstrate the effectiveness and the versatility of these silica-based products that can be used either in bulk and SPE cartridge media. We will investigate more the use of these products as strong cationic exchanger (SCX) for the “Catch and Release” purification of amine, their use as stationary phases for ion chromatography, their use as basic impurity scavengers, and also for more specific applications for organic synthesis chemistry like Suzuki coupling, amine free basing and Boc groups deprotection. |
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Asymmetric Reactions and Syntheses, Physical Organic Chemistry, Combinatorial Chemistry, Total Synthesis
8:00 PM-10:00 PM, Sunday, 26 March 2006 Georgia World Congress Center -- Ex. Hall B4, Poster
Division of Organic Chemistry |