Enantioselective catalytic C-H functionalization as a method for the synthesis of beta-amino acid derivatives

ORGN 579

Huw M. L. Davies, hdavies@acsu.buffalo.edu, Department of Chemistry, University at Buffalo, SUNY, Buffalo, NY 14260 and Aiwu Ni, pyridone@yahoo.com, Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY 14260.
Enantioselective C-H functionalization by means of rhodium carbenoid-induced C-H insertions has broad scope in organic synthesis. This presentation will highlight an effective method for the synthesis of beta-amino acid derivatives by Rh2(DOSP)4-catalyzed reactions of aryldiazoacetates with a cyclic silyl protected methylamine.

 

Heterocycles, Aromatics, Metal-Mediated Reactions and Syntheses, Materials, Devices, and Switches
8:00 PM-10:00 PM, Wednesday, 29 March 2006 Georgia World Congress Center -- Ex. Hall B4, Poster

Division of Organic Chemistry

The 231st ACS National Meeting, Atlanta, GA, March 26-30, 2006