Formation of functionalized cycloalkenes via intramolecular Morita–Baylis–Hillman alkylation using unsaturated thiol esters

ORGN 330

Kimberly A. Seibert, brookovr@chem.fsu.edu, Thomas F. N. Haxell, thaxell@chem.fsu.edu, and Marie E. Krafft, mek@chem.fsu.edu. Department of Chemistry, Florida State University, Tallahassee, FL 32306-4390
Recent advances in the intramolecular Morita–Baylis–Hillman reaction now permit the use of alkyl halides as the electrophilic partner forming functionalized cyclized products in excellent yield. The scope of this reaction has now been expanded to include reactions of unsaturated thiol esters.

 

New Reactions and Methodology, Bioorganic Chemistry, Molecular Recognition and Self Assembly
8:00 PM-10:00 PM, Tuesday, 28 March 2006 Georgia World Congress Center -- Ex. Hall B4, Poster

Sci-Mix
8:00 PM-10:00 PM, Monday, 27 March 2006 Georgia World Congress Center -- Ex. Hall B4, Sci-Mix

Division of Organic Chemistry

The 231st ACS National Meeting, Atlanta, GA, March 26-30, 2006