Diels-Alder reactions of a cyclopentadienone

ORGN 193

Michael Harmata, harmatam@missouri.edu and Maria G. Gomes, mgg5ff@mizzou.edu. Department of Chemistry, University of Missouri-Columbia, 601 S. College Avenue, Columbia, MO 65211
Diels-Alder adducts are formed when methyl-2-bromo-3-oxocyclopent-1-enecarboxylate is treated with electron-rich dienes and an amine base in refluxing THF or toluene. This reaction is regio- and diastereoselective. The scope of the reaction at its current state of development will be presented.

 

New Reactions and Methodology
8:00 AM-12:00 PM, Monday, 27 March 2006 Georgia World Congress Center -- C301, Oral

Division of Organic Chemistry

The 231st ACS National Meeting, Atlanta, GA, March 26-30, 2006