From hydrocarbons to carbohydrates: Design of novel cyclitols

ORGN 428

Goverdhan Mehta, gm@orgchem.iisc.ernet.in, Department of Organic Chemistry, Indian Institute of Science, Bangalore, 560012, India
We have been interested in transforming common, abundantly available hydrocarbons into diverse range of cyclitols and hexose sugars, through classical synthetic protocols, without recourse to biotransformations. In these endeavors, we have conceptualized several novel polycyclitols and annulated carbohydrates and this presentation would detail their syntheses. Employing the tool of carbocyclic ring annulation, a new family of surface modified carbohydrates and cyclitols with locked, axial rich conformations and bipolarofacial architecture has been created from tetralin and naphthalene. Similarly, cyclooctatetraene (COT) has been elaborated to a new family of homo-carbasugars. Synthesis and supramolecular architecture of these new entities will be discussed.
 

George A. Olah Award in Hydrocarbon or Petroleum Chemistry
8:10 AM-12:00 PM, Wednesday, 29 March 2006 Georgia World Congress Center -- Georgia Ballroom 2, Oral

Division of Organic Chemistry

The 231st ACS National Meeting, Atlanta, GA, March 26-30, 2006