ORGN 87 |
| Aromatic oxazolines are powerful compounds to introduce alkyl groups on an aromatic ring. Chiral applications of this process have shown to give good yields of the alkylated products but with only low to moderate diastereoselectivity. Improving the low diastereoselectivity of this methodology will be demonstrated using a chiral α,α-disubstituted amino acid as the basis for the chiral aromatic oxazolines formation. The improved chiral aromatic oxazoline rational and synthesis will be presented. |
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Asymmetric Reactions and Syntheses, Physical Organic Chemistry, Combinatorial Chemistry, Total Synthesis
8:00 PM-10:00 PM, Sunday, 26 March 2006 Georgia World Congress Center -- Ex. Hall B4, Poster
Division of Organic Chemistry |