CHED 415 |
| Good stereoselectivity has been reported in the addition of diazomethane to methylene derivatives of the chiral Meldrum's acid(1) which is formed through the condensation of malonic acid with menthone. An analogous chiral Meldrum's acid(2) has been prepared by the condensation of malonic acid with camphor. Investigation into the reactivity and stability of this new chiral camphor-derived Meldrum's acid was undertaken to determine if it would give the same degree of stereoselection as the menthone version, 1. The camphor-derived Meldrum's acid (2) has been found to be less stable under a variety of Knoevenagel condensation conditions.
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Undergraduate Research Poster Session: Organic Chemistry
11:00 AM-1:00 PM, Monday, 27 March 2006 Georgia World Congress Center -- Ex. Hall B4, Poster
Division of Chemical Education |
