CHED 427 |
| The condensation of 2-nitrobenzaldehyde with substituted diketones under Knoevenagel conditions (catalyst = piperidine/HOAc) leads to the expected 2-nitrobenzylidene derivatives, with the unexpected formation of substantial amounts of benzofuranyls as well. The formation of the benzofuranyls (for instance 1-(2-benzofuranyl)-ethanone from 2,4-pentanedione and the allyl ester of benzofurancarboxylilc acid from allyl acetoacetate) has proved to be perfectly general, significant amounts of the furanyls being formed in the case of six different substituted diketones. The products of the reaction have been characterized by GC-MS, H-NMR, C-NMR, and 2D-NMR. |
|
Undergraduate Research Poster Session: Organic Chemistry
11:00 AM-1:00 PM, Monday, 27 March 2006 Georgia World Congress Center -- Ex. Hall B4, Poster
Division of Chemical Education |