ORGN 564 |
| (Z)-1-Trimethylstannyl-1-alkenes easily prepared by the hydrozirconation of the corresponding 1-trimethylstannyl-1-alkynes followed by protonolysis with water, readily react with dichloroborane-dioxane complex in dichloromethane at room temperature for 8 h. The resulting solution is then treated with 1,3-propane diol at 0 oC for half an hour to provide the corresponding gem-dimetalloalkanes containing boron and tin. These alpha-trimethylstannylalkylboronate esters are obtained in high yields (70%-84%) and the structures of these novel intermediates are further confirmed by selective oxidation with alkaline hydrogen peroxide to provide the corresponding alcohols containing an alpha-trimethylstannyl group.
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Heterocycles, Aromatics, Metal-Mediated Reactions and Syntheses, Materials, Devices, and Switches
8:00 PM-10:00 PM, Wednesday, 29 March 2006 Georgia World Congress Center -- Ex. Hall B4, Poster
Division of Organic Chemistry |