MEDIWednesday, 31 August 2005

1:30 PM-4:30 PM Washington DC Convention Center -- Ballroom A, Oral
MC4R Agonists and Antagonists
Organizer, Presiding:R. P. Nargund
1:30 PMIntroductory Remarks
1:35 PMMelanotropin ligands for the hMC4Rs: Multiple biological activities! One receptor? The challenge!
Victor J. Hruby, Minying Cai, Jinfa Ying, Alexander Mayorov, Ravil Petrov, James Cain, Chad Park, Dev Trivedi
2:10 PMDesign of melanocortin receptor agonists by conformational restriction approach
Xinrong Tian, Adrian G. Switzer, Rajesh K. Mishra, Timothy Field, Steve A. Derose, Eric Hu, Denny Denton, Nick Kim, Adam W. Mazur, Frank H. Ebetino, John A. Wos, Doreen Crossdoersen, Beth B. Pinney, Julie A. Farmer, Russell L. Sheldon, Martin E. Dowty, Cindy M. Obringer, Annyodile Colson
2:45 PMQuinazolinone guanidines as MC4R agonists: SAR of unusual pharmacokinetic properties
Jason D Speake
3:20 PMDesign and syntheses of human Melanocortin subtype-4 receptor (hMC4R) agonists: Discovery of the tert-butylpyrrolidine archetype
Feroze Ujjainwalla
3:55 PMDesign, synthesis and characterization of potent and selective melanocortin-4 receptor antagonists
Chen Chen

Symposium Grid -- Division of Medicinal Chemistry -- Session Listing

The 230th ACS National Meeting, in Washington, DC, Aug 28-Sept 1, 2005