MEDIWednesday, 31 August 2005
1:30 PM-4:50 PM Washington DC Convention Center -- 206, Oral
Cysteine Protease Inhibitor Design
Organizer, Presiding:Steven O'Neill
1:30 PM267Mechanism-based approaches toward the design of cysteine protease inhibitors
James C. Powers, Amy J. Campbell
2:10 PM268Inhibitors of parasitic cysteine proteases: Homology modeling, de novo design and virtual screening
Mitchell A. Avery, Prashant V. Desai, Amar Chittiboyina, Akshay Patny, Anjaneyulu Sheri, Paulo Carvalho, Yogesh A Sabnis, Raji Reddy, Satish Goud Puppali, John M. Rimoldi, Anuradha Srivastava, Babu L. Tekwani, Jiri Gut, Philip J. Rosenthal
2:50 PM269Design and synthesis of medium-sized ring scaffolds as ICE inhibitors for treatment of inflammatory disease
John A. Wos, Steven V. O'Neil, David L Soper, Yili Wang, Michael C Laufersweiler, Kofi A Oppong, Christopher D Ellis, Thomas P Demuth, Biswanath De, Amy N Fancher, Wei Lu, Richard L Wang, William P Schwecke, Charles A Cruze, Maria Buchalova, David T Stanton, Katy L Davis, Gregory K Bosch, Kenetha J Stanton, Steven M Berberich, Marina Belkin
3:30 PM270Pyrimidoindolones as potent non-peptidic inhibitors of caspase-3
Lisa M. Havran, Chae-Koo Dan Chong, Ann Aulabaugh, Helen Chan, Wayne Childers, Julia Cho, Rebecca Cowling, Paul J Dollings, Myles Fennel, Boyd L. Harrison, Wah-Tung Hum, Bhupesh Kapoor, Huai-Ping Ling, Ronald L. Magolda, Vasilios Marathias, Lidia Mosyak, Franklin Moy, Albert J. Robichaud, Gregory J. Tawa, Desiree Tsao, Andrew Wood, Weixin Xu
4:10 PM271Design, synthesis and pharmacology of potent azepanone-based inhibitors of the cysteine protease cathepsin K
Robert W. Marquis

Symposium Grid -- Division of Medicinal Chemistry -- Session Listing

The 230th ACS National Meeting, in Washington, DC, Aug 28-Sept 1, 2005