Reduction and iodinolysis of homopropargyl alcohols

ORGN 384

Kathlyn A. Parker, Kathlyn.Parker@sunysb.edu and Hong Zhao, hzhao@ic.sunysb.edu. Department of Chemistry, State University of New York at Stony Brook, 700 Northloop Road, Stony Brook, NY 11790
Several Z-vinyl iodides were prepared by reduction and iodinolysis of homopropargyl alcohols. Lithium aluminum hydride was used as both metalating agent and reductant. The reactions were largely dependent on the structure of the homopropargyl alcohols. For each substrate, reaction conditions were optimized for temperature and time. The scope and limitations will be discussed.

 

Bioorganic, Metal-Mediated Reactions, and Molecular Recognition
8:00 PM-10:00 PM, Tuesday, 30 August 2005 Washington DC Convention Center -- Hall A, Poster

Division of Organic Chemistry

The 230th ACS National Meeting, in Washington, DC, Aug 28-Sept 1, 2005