ORGN 415 |
| The synthesis of short chain water-soluble polymers of high monodispersity is a challenging task that requires careful control over the reaction process. At the same time, these short-chain polymers have profoundly different properties including the biological function than their long-chain analogs. Herein, we describe biomimetic nanosize reactors devised for synthesis of such polymers. These reactors are based on functional liposomes that provide a confined reaction space and can trigger the polymerization process. The size of the polymer is controlled by the concentration of the monomer inside the reactor whereas its dispersity depends on the uniformity of the liposomes. A model polymerization reaction of cellobiosyl fluoride was used to prove the feasibility of our approach. The system design, development and outcome of the new approach to the polymerization will be discussed.
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Bioorganic, Metal-Mediated Reactions, and Molecular Recognition
8:00 PM-10:00 PM, Tuesday, 30 August 2005 Washington DC Convention Center -- Hall A, Poster
Division of Organic Chemistry |
