ORGN 264 |
| Current research in our lab on the synthesis of rigid molecular scaffolds and amphiphilic catenanes will be introduced. Molecular scaffolds are molecules that provide multiple functional groups that act as points of attachment to a variety of groups or biologically significant moieties. We have designed two isomeric scaffolds, each bearing a rigid perhydrophenalene core, which will be studied as template-assisted synthetic proteins (TASPs) and Gemini surfactant cores. Progress on two distinct synthetic routes will be presented. Synthesis and studies on a number of amphiphilic catenanes will also be discussed. Our catenanes are rendered amphiphilic by the attachment of one or more hydrophobic units to a polar [2]catenane head-group. |
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Molecular Recognition and Materials
1:00 PM-4:40 PM, Monday, 29 August 2005 Washington DC Convention Center -- 201, Oral
Division of Organic Chemistry |