ORGN 666 |
| Enantiomerically pure β-amino acids and their derivatives are important building blocks for the synthesis of β-peptides, β-lactam antibiotics and many important drugs. Recently, an efficient approach for the synthesis of protected β-amino acid derivatives has been developed in our group. Enamine substrates can be easily obtained through a one-step synthesis from the corresponding β-keto esters. The catalytic asymmetric hydrogenation afforded the desired products in high enantioselectivities
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Asymmetric Reactions, Heterocycles, Aromatics, Combinatorial, and Physical Organic Chemistry
8:00 PM-10:00 PM, Wednesday, 31 August 2005 Washington DC Convention Center -- Hall A, Poster
Division of Organic Chemistry |
