CHED 216 |
| Amino acids are vital to biological processes therefore the development of artificial receptors is of great concern in supramolecular chemistry. We have proposed that molecules composed of a binaphthyl core bearing symmetrical aza-15-crown-5 groups and identical ammonium carboxylate receptor moieties will bind unprotected á amino acids in a complementary manner in the presence of sodium but not in the presence of potassium. This selectivity is due to the binding stoichiometry of aza-15-crown-5, which binds sodium in a 1:1 ratio while binding potassium in a 2:1 ratio. Binding of the ions induces conformational changes in the binaphthyl core that allows for binding in the presence of sodium but not in the presence of potassium. This work will detail the synthesis of such compounds along with their affinity towards amino acids in both sodium and potassium salt solutions and ability to transport bound amino acids across liquid membranes.
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Undergraduate Research Poster Session: Organic Chemistry
2:00 PM-4:00 PM, Monday, 29 August 2005 Washington DC Convention Center -- Hall A, Poster
Division of Chemical Education |
