(NHC)Cu(I)-Catalyzed (NHC = N-Heterocyclic Carbenes) hydrosilylation of hindered and functionalized carbonyl compounds

ORGN 377

Silvia Díez-González, sdiezgon@uno.edu1, Natalie M Scott1, Edwin D. Stevens, estevens@uno.edu1, and Steven P. Nolan, snolan@iciq.es2. (1) Chemistry Department, University of New Orleans, 2000 Lakeshore Drive, New Orleans, LA 70148, (2) Nolan group, Institut of Chemical Research of Catalonia (ICIQ), Av. Països Catalans, 16, 43007 Tarragona, Spain
Copper, an inexpensive metal source, and NHC (N-heterocyclic carbenes) as ligands, have been used for the hydrosilylation of different carbonyl compounds. In situ generated or well-defined (NHC)copper(I), neutral and cationic, complexes have been studied. Several carbonyl compounds, functionalized and/or sterically hindered, have been efficiently hydrosilylated under these conditions. Diastereoselectivity and mechanistic aspects of this transformation will be discussed.

 

Bioorganic, Metal-Mediated Reactions, and Molecular Recognition
8:00 PM-10:00 PM, Tuesday, 30 August 2005 Washington DC Convention Center -- Hall A, Poster

Division of Organic Chemistry

The 230th ACS National Meeting, in Washington, DC, Aug 28-Sept 1, 2005