ORGN 702 |
| Starting from resin-bound benzimidazoles, we will present efficient approaches for the parallel solid-phase synthesis of trisubstituted triazinobenzimidazolediones (1) and 2-imino-4-oxo-1,3,5-triazino[1,2-a]benzimidazoles (2). Compounds (2) were obtained via tandem Aza-Wittig/heterocumulene-mediated annulation reaction. Using halogenoalkyl isocyanates, the Aza-Wittig/heterocyclization reaction was extended for the synthesis of unique tetracyclic benzylimidazoles systems (3).
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Combinatorial, Parallel, and Solid-Phase Chemistry
8:00 AM-11:00 AM, Thursday, 1 September 2005 Washington DC Convention Center -- Ballroom C, Oral
Division of Organic Chemistry |
