An introduction to fluorous techniques for the synthesis of small organic molecules

ORGN 208

Dennis P. Curran, Department of Chemistry, University of Pittsburgh, Chevron Science Center, 219 Parkman Avenue, Pittsburgh, PA 15260
This lecture will serve as an introduction to the symposium on “Recent Advances in Fluorous Chemistry” It features a diverse selection of recently introduced fluorous techniques unified by the theme of strategic synthesis and separation. Separation techniques include liquid-liquid extraction, solid-liquid extraction and chromatography over fluorous silica gel. Featured are fluorous monophasic, biphasic and triphasic reactions along with the use of fluorous reagents, reactants, scavengers and protecting groups in traditional, solution phase parallel and mixture synthesis. The ease of separation and product recovery make fluorous methods attractive for large scale chemistry while their speed and reliability are strong assets for small scale chemistry.
 

Recent Advances in Fluorous Chemistry
8:00 AM-12:00 PM, Monday, 29 August 2005 Washington DC Convention Center -- Ballroom C, Oral

Division of Organic Chemistry

The 230th ACS National Meeting, in Washington, DC, Aug 28-Sept 1, 2005