Palladium-catalyzed intramolecular cyclizations of aryl allyl ethers and aryl homoallyl ethers for the synthesis of benzofuran and chromene derivatives

ORGN 386

So Won Youn, so_wony@hotmail.com and Jeong Im Eom. Department of Chemistry, Pukyong National University, Busan, 608-737, South Korea
The construction of cyclic compound via transition metal catalysts is of currently considerable interest in organic chemistry. Treatment of aryl allyl ethers with Pd(CH3CN)2Cl2, p-benzoquinone and Na2CO3 under mild condition afforded in situ the benzofurans via Claisen rearrangement. On the other hand, aryl homoallyl ethers gave the chromenes through the direct cyclizations in the similar conditions. Pd-catalyzed intramolecular cyclizations were performed with a variety of aryl allyl ethers and aryl homoallyl ethers to provide the corresponding benzofuran and chromene derivatives

 

Bioorganic, Metal-Mediated Reactions, and Molecular Recognition
8:00 PM-10:00 PM, Tuesday, 30 August 2005 Washington DC Convention Center -- Hall A, Poster

Division of Organic Chemistry

The 230th ACS National Meeting, in Washington, DC, Aug 28-Sept 1, 2005