Fluorescent total synthesis of natural products

ORGN 30

James J La Clair, i@xenobe.org, Xenobe Research Institute, P.O. Box 4073, San Diego, CA 92164-4073
The development of total synthesis has traditionally been guided by the preparation of rare natural products or through the development of methodology. Once a total synthesis is complete, subsequent and often collaborative analyses are used to detail the cellular and molecular function of a targeted natural product. The synthesis and semi-synthesis of analogs are often prepared to enhance these studies. While often entrained by discipline, the asyntactic organization of biological and synthetic studies offers an enhanced venue for the continued development of complex molecule total synthesis. In this presentation, we directly fuse total synthesis with molecular - cell biological studies to provide a hybrid system that places synthetic efforts akin with molecular and cellular biology.

 

Total Synthesis of Complex Molecules
8:00 AM-12:00 PM, Sunday, 28 August 2005 Washington DC Convention Center -- 202B, Oral

Division of Organic Chemistry

The 230th ACS National Meeting, in Washington, DC, Aug 28-Sept 1, 2005