ORGNTuesday, 15 March 2005

1:00 PM-4:20 PM Convention Center -- Room 11A, Oral
Process R&D, Practical Synthesis, and Methodology
Presiding:Lushi Tan
1:00 PMGreen technology in pharmaceutical process development: Application in the synthesis of Acetaminophen, Ibuprofen and heterocycles
Apurba Bhattacharya, Victor H Suarez, Victoriano Tamez, Nitinchandra Patel, Frank Rinaldi, John A. Grosso
1:20 PMZn-CuI-Mediated coupling of alkyl halides with vinyl sulfones, vinyl sulfonates and vinyl sulfonamides
Matthew M. Zhao, Chuanxing Qu, Joseph E. Lynch
1:40 PMNovel synthesis of substituted homochiral pyrrole derivatives
Ayhan S. Demir
2:00 PMBronsted acid-catalyzed amidation of imines
Jon C. Antilla, Haile Zhang, Yong Wang, Emily B. Rowland, Gerald B. Rowland
2:20 PMStereoselective synthesis of densely functionalized bicyclo[3.1.0]hexane mGluR2 agonists
Frederick W. Hartner, Lushi Tan, Nobuyoshi Yasuda, Naoki Yoshikawa, Kan K. Eng, William R. Leonard Jr., Fuh-Rong Tsay, Ralph P. Volante
2:40 PMProcess research for the synthesis of RWJ-56423
Michael Breslav, Bruce Harris, Birdella Kenney, Cynthia A. Maryanoff, Frank J. Villani Jr., Fan Zhang-Plasket, H. Marlon Zhong
3:00 PMDevelopment of a practical asymmetric synthesis of a DP receptor antagonist
Zhihui Peng, Mike Hillier, Guy Humphrey, Michel Journet, Jeff Kuethe, Peter Maligres, Jeff Marcoux, Chris McWilliams, David Tellers, Audrey Wong, Ed Grabowski, Dave Hughes
3:20 PMDiscovery, implementation, and mechanism of a pressure-dependent catalytic, asymmetric α,β-unsaturated carboxylic acid hydrogenation
David M. Tellers, J. Chris McWilliams, Guy Humphrey, Michel Journet, Yongkui Sun
3:40 PMA novel concise total synthesis of the quinazoline alkaloids
Ji-Feng Liu, Ping Ye, Mira Kaselj, Kevin Sprague II, Katie Sargent, Yuko Isome, Bailin Zhang, Grace Bi, Daniel Yohannes, Libing Yu, Carmen M. Baldino
4:00 PMBILN2061 synthesis: Development of practical processes for the synthesis of the quinoline subunit and its coupling to the macrocyclic core
Rogelio P. Frutos, Pierre Beaulieu, Vittorio Farina, Michael Johnson, Nizar Haddad, Ioannis Houpis, Nathan Yee, Chris Senanayake
Paper Withdrawn
Paper Withdrawn

Symposium Grid -- Division of Organic Chemistry -- Session Listing

The 229th ACS National Meeting, in San Diego, CA, March 13-17, 2005