MEDIThursday, 17 March 2005

9:00 AM-12:00 PM Convention Center -- Room 6C, Oral
From Bench to Pilot Plant: Sponsored by Teledyne Isco, Inc
Organizer:Les McQuire
9:00 AMIntroductory Remarks
9:05 AMPractical asymmetric synthesis of a potent PDE4 inhibitor via stereoselective enolate alkylation of a chiral aryl-heteroaryl secondary tosylate
Cheng-yi Chen, Paul D. O'Shea, Weirong Chen, Philippe Dagneau, Lisa F. Frey, Edward J. J. Grabowski, Karen M Marcantonio, Robert A. Reamer, Lushi Tan, Richard D. Tillyer, Amelie Roy, Xin Wang, Dalian Zhao
9:40 AMApplication of new technologies in pharmaceutical process research and development
Jennifer L. Rutherford
10:15 AMEnzymatic synthesis of pharmaceutical intermediates
Brian Morgan, Grace DeSantis, Nelson Barton, David P. Weiner, William A. Greenberg, Mark J. Burk
10:50 AMEvolution of a manufacturing route for a highly potent drug candidate
Ambarish K. Singh
11:25 AMFrom deep-sea sponge to pilot plant: The large scale total synthesis of the marine natural product (+)-Discodermolide
Stuart J. Mickel

Symposium Grid -- Division of Medicinal Chemistry -- Session Listing

The 229th ACS National Meeting, in San Diego, CA, March 13-17, 2005