ORGN 399 |
| A method will be described that allows one to systematically add new building blocks to the genetic codes of living organisms. Over thirty unnatural amino acids have been genetically encoded in both prokaryotic and eukaryotic organisms in response to both three and four base codons with high efficiency and fidelity. These include photoreactive, redox active and fluorescent amino acids, amino acids with unique chemical reactivity, and heavy atom containing amino acids. This expanded genetic code may allow the generation of proteins and possibly entire organism with novel properties not restricted by the common twenty amino acids. |
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Ronald Breslow Award for Achievement in Biomimetic Chemistry
1:40 PM-5:05 PM, Tuesday, 15 March 2005 Convention Center -- Ballroom 20 C-D, Oral
Division of Organic Chemistry |